Description
Kisspeptin 5mg — Lyophilized Research Peptide for KISS1R & Reproductive-Axis Studies
Kisspeptin 5mg is a lyophilized research peptide commonly used to investigate
KISS1/KISS1R (GPR54) signaling and downstream hypothalamic–pituitary–gonadal (HPG) axis
biomarker responses. Each vial contains 5mg with ≥99% purity and a lot-specific COA available.
Kisspeptin is a KISS1-derived neuropeptide family studied for its role as an upstream regulator of
GnRH neuron activity and related endocrine signaling. In laboratory settings, kisspeptin peptides are
frequently used as tools to explore reproductive neuroendocrinology, puberty-related signaling, and hormone-axis feedback
under controlled experimental conditions.
What It Is
- Class: Neuroendocrine signaling peptide (KISS1-derived; KISS1R agonist in research models)
- Core research roles: Experimental probe for GnRH-linked signaling, pituitary gonadotropin readouts, and reproductive-axis feedback mechanisms
- Research focus: HPG-axis biomarkers (model-dependent), neuroendocrine regulation, and signaling-network mapping
Proposed Mechanisms & Pathways (Preclinical)
KISS1R (GPR54) Signaling
- Studied as a ligand system for KISS1R, a receptor commonly investigated in reproductive-axis and neuroendocrine research.
- Used to probe intracellular signaling cascades and transcriptional responses downstream of receptor activation (assay/model dependent).
- Often evaluated alongside neuroendocrine network inputs that regulate timing and amplitude of signaling responses in experimental designs.
HPG Axis & Hormone-Linked Readouts
- Commonly used in models exploring GnRH neuron activation and downstream endocrine biomarker panels (e.g., gonadotropin-related readouts).
- Included in research examining puberty and reproductive signaling pathways and feedback regulation.
- Sometimes studied in broader contexts linking neuroendocrine signaling with stress or metabolic markers (study dependent).
Selected Research Highlights
- Neuroendocrine Regulation: Frequently used to study upstream control of reproductive-axis signaling and associated biomarker responses.
- Puberty & Fertility Models: Incorporated into experimental paradigms examining developmental and reproductive signaling pathways.
- Pathway Mapping: Used as a mechanistic tool to evaluate receptor-driven signaling, gene expression panels, and endocrine feedback relationships.
Chemical & Handling Information
- Type: Kisspeptin (KISS1-derived research peptide)
- Note on variants: Kisspeptin research may use different fragments (e.g., KP-10 / KP-54). Confirm the exact sequence in the lot documentation/COA for your specific vial.
- Appearance: White to off-white lyophilized powder (hygroscopic; handle promptly)
Specifications
- Compound: Kisspeptin
- Amount: 5mg per vial
- Form: Lyophilized powder
- Purity: ≥99% (HPLC); COA per lot available
- Packaging: Sealed vials suitable for standard laboratory handling
- Lab testing: View Lab Test
Storage & Stability
- Store lyophilized vials in a cool, dry place, protected from light and moisture.
- Refrigeration or freezing of the lyophilized material is recommended for extended stability, according to laboratory SOPs.
- After reconstitution, store at 2–8 °C for short-term use.
- For longer-term storage, aliquot and freeze at ?20 °C or below; avoid repeated freeze–thaw cycles.
FAQ
How much kisspeptin is in each vial?
Each vial contains 5mg of lyophilized kisspeptin research material.
Is a COA available?
Yes—purity is listed as ≥99% (HPLC) with a lot-specific COA available. You can link to your Lab Tests page for details.
Research use only. Not for human or veterinary use. For Kisspeptin 5mg research vials, visit
MyPurePeptide.com.
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