Description
SLU-PP-332 5mg — Pan-ERR (ERR?/ERR?/ERR?) Agonist for Mitochondrial & Metabolic Research
SLU-PP-332 5mg is a small-molecule research compound studied as a pan estrogen-related receptor (ERR) agonist
(ERR?/ERR?/ERR?). In preclinical research, ERR agonism is used to explore mitochondrial gene programs, oxidative metabolism pathways,
energy expenditure, and fatty-acid oxidation. Each vial contains 5mg with ≥99% purity and a lot-specific COA available.
Estrogen-related receptors (ERRs) are orphan nuclear receptors that regulate transcriptional programs involved in cellular
energy metabolism, including pathways linked to mitochondrial biogenesis, oxidative phosphorylation, and lipid utilization.
SLU-PP-332 is used in research settings as a tool to probe ERR-driven metabolic adaptation and exercise-associated
transcriptional signatures in controlled experimental models.
What It Is
- Class: Small-molecule nuclear-receptor agonist (pan-ERR agonist)
- Primary targets (research): ERR?, ERR?, ERR?
- Research focus: Mitochondrial function, oxidative metabolism, fatty-acid oxidation, exercise-mimetic transcriptional programs, and metabolic biomarker readouts (model dependent)
Proposed Mechanisms & Pathways (Preclinical)
ERR Activation & Gene Programs
- Investigated for activation of ERR-regulated transcription linked to oxidative metabolism and mitochondrial pathway markers.
- Used to study downstream gene-expression patterns associated with aerobic/oxidative capacity in research models.
- Frequently evaluated alongside co-regulator biology (e.g., PGC-1–linked networks) in mechanistic metabolic research.
Mitochondrial & Metabolic Readouts
- Studied in vitro for changes in mitochondrial respiration and related bioenergetic readouts.
- In mouse metabolic-disease models, reported outcomes include changes in energy expenditure, fatty-acid oxidation, and body-composition-related endpoints (study dependent).
- Common readouts include indirect calorimetry markers (e.g., fuel utilization shifts), lipid metabolism panels, and pathway-protein/gene markers depending on study design.
Selected Research Highlights
- Metabolic Syndrome Models: Used in preclinical studies assessing energy expenditure, lipid utilization, adiposity-related measures, and insulin-sensitivity readouts.
- Exercise-Associated Signaling: Included in research evaluating ERR-dependent aerobic/exercise-like transcriptional programs and performance-linked endpoints in animal studies.
- Mitochondrial Bioenergetics: Applied in cellular systems to probe respiration-related outcomes and oxidative metabolism markers.
Chemical & Handling Information
- Compound: SLU-PP-332
- Type: Small-molecule research compound
- Chemical name (reference): (E)-4-Hydroxy-N’-(naphthalen-2-ylmethylene)benzohydrazide
- CAS (reference): 303760-60-3
- Appearance: Solid powder (handle promptly; minimize moisture exposure)
- General handling: Protect from moisture, heat, and light during routine laboratory handling; prepare solutions per laboratory SOPs and lot documentation.
Specifications
- Compound: SLU-PP-332
- Amount: 5mg per vial
- Form: Solid powder
- Purity: ≥99% (HPLC); COA per lot available
- Packaging: Sealed vials suitable for standard laboratory handling
Storage & Stability
- Store dry vials in a cool, dry place, protected from light and moisture.
- For extended stability, store at ?20 °C per laboratory SOPs.
- After preparing solutions, store at 2–8 °C for short-term use.
- For longer-term storage, aliquot and freeze at ?20 °C or below; avoid repeated freeze–thaw cycles.
FAQ
What is SLU-PP-332 used for in research?
SLU-PP-332 is used as a research tool to study ERR?/ERR?/ERR?-linked transcription, mitochondrial bioenergetics markers, and metabolic readouts in controlled preclinical models.
How much is in each vial?
Each vial contains 5mg of SLU-PP-332.
Is a COA available?
Yes—purity is listed as ≥99% (HPLC) with a lot-specific COA available. You can link users to your Lab Tests page.
Research use only. Not for human or veterinary use. For research materials, visit
MyPurePeptide.com.
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