SS-31 10 mg

SS-31 (Elamipretide) 10 mg — Mitochondria-Targeting Peptide for Cellular Energy & Aging Research

SS-31 (Elamipretide) is a mitochondria-targeting tetrapeptide widely studied in laboratory models of
mitochondrial dysfunction, cellular bioenergetics, and oxidative stress.
SS-31 is commonly described as associating with cardiolipin in the inner mitochondrial membrane, where it is explored for supporting
mitochondrial membrane structure (cristae), improving respiratory efficiency, and reducing stress-related ROS signaling.
For SEO and literature cross-referencing, SS-31 may also appear as Elamipretide, MTP-131, or Bendavia.

What It Is

• Class: Mitochondria-targeting tetrapeptide (SS-31 / Elamipretide)
• Also known as: SS-31, Elamipretide, MTP-131, Bendavia
• Concept: Research tool for studying cardiolipin-linked mitochondrial membrane stability,
  ATP-linked bioenergetics, and redox/oxidative-stress pathways

Proposed Mechanisms (Preclinical)

Common Research Applications

• Mitochondrial Function: cardiolipin biology, mitochondrial membrane integrity, cristae organization, and respiration assays
• Cellular Energy & ATP: oxidative phosphorylation, bioenergetic capacity, fatigue/energy modeling endpoints
• Oxidative Stress: ROS signaling, redox homeostasis, mitochondrial stress markers
• Aging Biology: age-associated mitochondrial decline, exercise tolerance, metabolic resilience in aged models
• Muscle Research: skeletal muscle energetics, endurance readouts, mitochondrial quality control
• Cardiac Research: cardiomyopathy models, mitochondrial efficiency, supercomplex organization (model-dependent)
• Kidney Research: ischemia/reperfusion stress models, mitochondrial protection pathways (preclinical)
• Neuro & Brain Research: mitochondrial stress in neurodegeneration and injury models (preclinical)
• Vision & Retina Research: retinal ganglion cell stress models (e.g., glaucoma paradigms) and clinical research programs in dry AMD/GA (literature referenced)

Selected Research Highlights

• Cardiolipin-Linked Mitochondrial Support: Commonly discussed as a cardiolipin-associating peptide studied for inner-membrane structure and respiration efficiency.
• Exercise / Aging Models: Explored in aged-animal studies examining redox stress and exercise-tolerance endpoints.
• Mitochondrial Myopathy Research: Evaluated in human research settings for functional and bioenergetic outcomes in mitochondrial disease populations.
• Heart & Cardiomyopathy Models: Studied in mitochondrial cardiomyopathy contexts where cardiolipin biology is central (model-dependent).
• Kidney Stress Models: Investigated in preclinical renal injury paradigms focused on mitochondrial ROS and structural preservation.
• Ocular / Vision Research: Studied in retinal-function paradigms (including glaucoma-related models) and evaluated in clinical research for dry AMD with geographic atrophy.

Chemical & Handling Information

• Type: Synthetic mitochondria-targeting peptide (SS-31 / Elamipretide)
• Peptide length: 4 amino acids (tetrapeptide)
• Appearance: White to off-white lyophilized powder

Specifications

• Peptide: SS-31 (Elamipretide)
• Amount: 10 mg per vial
• Form: Lyophilized powder
• Purity: ?99% (HPLC); COA per lot available
• Packaging: Sealed vials suitable for standard laboratory handling

Storage & Stability

• Store lyophilized vials in a cool, dry place, protected from light.
• For extended stability, keep vials refrigerated or frozen as per laboratory SOPs.
• After reconstitution, store at 2–8 °C for short-term use.
• For long-term storage, aliquot and freeze at ?20 °C or below; avoid repeated freeze–thaw cycles.

Disclaimer: For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.