What Is Selank?

Selank is a synthetic peptide compound discussed in scientific and translational literature as a neuroactive agent, often framed around stress adaptation and
anxiety-like response models. The overall evidence base varies by region and study design, so it’s best interpreted through a research lens.
This page focuses only on subcutaneous (subQ) administration context.

What Is Semax?

Semax is a synthetic peptide compound derived from an ACTH fragment (commonly described as an ACTH(4–10) analogue in the literature).
It is frequently discussed in research contexts related to cognition, attention, neurotrophic signaling themes, and neurological recovery models.
This page focuses only on subcutaneous (subQ) administration context.

Selank vs Semax: Key Differences

• Discussion focus: Selank is typically framed around calm/stress adaptation; Semax is commonly framed around focus/mental performance themes.
• “Feel” in anecdotes: Selank is often described as smoother; Semax is often described as more activating (individual response varies).
• Category: These are discussed as neuroactive peptides, not structural tissue-repair peptides.

How They Work (Mechanism Themes)

Selank (themes discussed in research)

• Modulation of neurotransmitter-related signaling and stress-response pathways has been discussed in multiple publications.
• Some work explores immune/inflammatory signaling interactions depending on model and endpoints.

Semax (themes discussed in research)

• Often discussed in relation to neurotrophic signaling themes (commonly referenced: BDNF/NGF-related pathways in various research contexts).
• Explored in neurologic injury models and neuroprotection-oriented endpoints (study design varies widely).

Note: Mechanism themes do not guarantee outcomes. Study endpoints, population, duration, and design matter.

Potential Benefits Reported in Research Context

Selank – commonly discussed research directions

• Stress response modulation: Frequently framed around calming/adaptation in stress models.
• Emotional steadiness: Sometimes discussed as improved baseline regulation in certain contexts.
• Secondary sleep support: Sometimes discussed indirectly (often via reduced stress perception).

Semax – commonly discussed research directions

• Focus and cognitive performance: Often discussed around attention/clarity themes.
• Neuro-signaling support: Research explores neurotrophic and recovery-oriented signaling endpoints.
• Mental stamina: Commonly discussed outcome theme in performance-style contexts (varies by model).

What Research Says

Publicly accessible research includes a mix of preclinical, translational, and region-specific clinical discussions. Evidence strength depends on the question being asked
(endpoint measured, duration, and population). When interpreting findings, prioritize primary literature and clearly defined endpoints.

• Best practice: evaluate study design, dose context, duration, and measured outcomes.
• Reality check: positive findings in one model may not translate to different populations or goals.

Dosing & Administration (SubQ Only – Research Context)

This section is for educational/research interpretation only. There is no universally accepted human subQ dosing standard for these compounds.
When dosing is discussed, it should be taken from a documented protocol and interpreted with appropriate professional oversight.

Selank (subQ context)

• No universal standard: subQ protocols vary by source and research context.
• Common pattern in discussions: “course-style” use is frequently mentioned (finite duration rather than indefinite use).
• Math matters: Use a consistent mg-to-mL conversion process (see Math & Conversions).

Semax (subQ context)

• No universal standard: subQ protocols vary by research goal and source context.
• Common pattern in discussions: many protocols are described as short cycles with breaks rather than constant use.
• Track response: focus, sleep quality, headaches, and restlessness are frequently tracked variables.

If you need help converting protocol dosing to syringe units, use our Math & Conversions guide.

Safety, Side Effects & Regulatory Status

• Regulatory status varies: approval/indications are not uniform across countries.
• Commonly discussed side effects (anecdotal): headache, restlessness, sleep disruption, and injection-site irritation.
• Not well established: pregnancy/breastfeeding and pediatric use are commonly listed as not established.
• Quality matters: use identity/purity documentation (COA) and ensure appropriate handling/storage.

Timeline & What People Ask About

“How fast does it work?” is one of the most searched questions. In anecdotes, Semax is often described as more noticeable in short windows,
while Selank is often described as more subtle and baseline-oriented. Research timelines depend on endpoints measured and protocol duration.

Stacking & Comparison Notes

These compounds are typically discussed as neuroactive peptides. When people discuss pairing them, the theme is often “calm baseline + focus window,”
but controlled evidence for stacking is limited. Many prefer testing one variable at a time.

• Practical caution: stacking can make it harder to identify what is helping (or what is causing side effects).
• Simple approach: change one thing at a time and track mood, focus, and sleep.

Frequently Asked Questions