Description
Ipamorelin 10 mg — Selective GHRP-Class Peptide for GH Secretion Research
Ipamorelin is a synthetic pentapeptide classified as a
growth hormone–releasing peptide (GHRP)-type analog. It is investigated in
preclinical and exploratory clinical research as a selective growth hormone
secretagogue with reduced off-target activity at receptors such as ACTH and cortisol
pathways, compared with earlier GHRPs.
What It Is
- Class: GHRP-class growth hormone secretagogue
- Peptide length: 5 amino acids (pentapeptide)
- Research focus: Pituitary GH release, GH/IGF-1 axis behavior, and
combination protocols with GHRH analogs.
Proposed Mechanisms (Preclinical)
GH Secretagogue Receptor (GHS-R) Activation
- Acts at the growth hormone secretagogue receptor (GHS-R),
related to the endogenous ligand ghrelin. - Stimulates pulse-like GH release from the pituitary in
experimental models. - Designed for greater selectivity with less activation of
ACTH/cortisol pathways than some earlier GHRPs.
GH/IGF-1 Axis & Body-Composition Research
- Used in studies assessing GH and IGF-1 profiles over time.
- Model-dependent exploration of changes in lean mass, fat mass, and
recovery markers when combined with training or other interventions. - Frequently paired with GHRH analogs (e.g., CJC-1295 variants)
in research protocols to examine synergy.
Selected Research Highlights
- GH Secretion: Ipamorelin has been studied for its ability to
increase GH in a pulsatile fashion, with interest in a more selective side-effect
profile versus earlier GHRP compounds. - Endocrine Selectivity: Experimental and early clinical data examine
ACTH, cortisol, and prolactin responses to characterize its endocrine selectivity. - Body-Composition & Recovery Models: Research in animals and
small human cohorts has explored markers of body composition, strength, and recovery,
typically as exploratory endpoints.
Chemical & Handling Information
- Type: Synthetic GHRP-class pentapeptide
- Appearance: White to off-white lyophilized powder
Specifications
- Peptide: Ipamorelin
- Amount: 10 mg per vial
- Form: Lyophilized powder
- Purity: ?99% (HPLC); COA per lot available
- Packaging: Sealed vials suitable for standard laboratory handling
Storage & Stability
- Store lyophilized vials in a cool, dry place, protected from light.
- Refrigeration or freezing of the lyophilized peptide is recommended for extended stability,
according to laboratory SOPs. - After reconstitution, store at 2–8 °C for short-term use.
- For long-term storage, aliquot and freeze at ?20 °C or below; avoid repeated freeze–thaw cycles.
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