DSIP 10 mg

DSIP is a synthetic linear nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, prepared by solid-phase peptide synthesis and supplied as the free acid. The sequence is unmodified at both termini, carrying a free N-terminal tryptophan and a free C-terminal glutamic acid. It contains no cysteine and forms no intramolecular disulfide bond, so the material exists as a single- chain, non-cyclised peptide.

No receptor has been isolated for this nonapeptide and it is not assigned to a defined receptor class in the chemical literature. Where a molecular target is examined analytically, engagement is measured in cell-free radioligand displacement panels and in membrane preparations from cell lines transfected with candidate G-protein-coupled receptors, with the readout expressed as specific counts displaced at a fixed peptide concentration. Binding constants derived this way are the terminal measurement; the material carries no established target assignment beyond them.

Primary literature on this molecule addresses its isolation chemistry, solid-phase synthetic routes, and analytical characterisation by HPLC, mass spectrometry and NMR, together with cell-free binding- panel reports. Search results and cited literature do not establish the performance of a commercial lot or a use recommendation.