Retatrutide 10mg Research Material

Q: What is the intended use of this material?

It is supplied for laboratory research and analytical work only and is not intended for human or veterinary use.

Q: What analytical identity data accompanies the vial?

The per-lot certificate of analysis reports HPLC purity with the chromatogram, mass confirmation against the calculated molecular weight, appearance, and the lot identifier printed on the vial label for traceability.

Retatrutide 10mg

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Research profileLab documentation

Retatrutide 10mg listing: single lyophilized vial, purity documented by per-lot HPLC COA, identity data, storage guidance and U.S. fulfillment. Lab use only.

MaterialRetatrutide 10mg

Amount10mg per vial

FormLyophilized powder

Purity≥99% by HPLC · per-lot COA

StorageUnopened vial: store sealed, dry, and protected from light at controlled room temperature or refrigerated. After opening or reconstitution: keep refrigerated at 2–8 °C.

In stock · Fulfilled from Austin, TexasMost in-stock orders are usually processed within 1 business day after order review and payment approval.

CompoundRetatrutide (LY3437943, acylated 39-residue synthetic peptide)

CAS2381089-83-2

Purity≥99% by HPLC · per-lot COA

Physical formLyophilized powder

Amount10mg per vial

StorageUnopened vial: store sealed, dry, and protected from light at controlled room temperature or refrigerated. After opening or reconstitution: keep refrigerated at 2–8 °C.

Current lot documentation

Submitted sample & third-party report

Review the submitted sample image and current laboratory report, then verify the record directly with Janoshik.

Verify on Janoshik

Janoshik submitted sample image for current lot — Submitted vial / sample

Current third-party COA report — Laboratory report

LaboratoryJanoshik

Task#216334

Test dateAug 10, 2026

Verification keyHQAJ1DQ1CAGP

Measured content11.04mg

HPLC purity99.095%

Endotoxin1.838 EU/vial · Task #216335

The complete third-party report is the controlling source for the analytical results shown for this lot.

Retatrutide is a synthetic 39-amino-acid peptide built on a glucose-dependent insulinotropic polypeptide (GIP) backbone, carrying α-aminoisobutyric acid (Aib) substitutions at positions selected for conformational constraint and protease resistance. A C20 diacid lipid chain is attached at a lysine side chain through a γ-glutamate and OEG spacer arrangement. The molecule is a single-chain, C-terminally amidated peptide with one defined acylation site.

Three class B1 G-protein-coupled receptors are the molecular targets characterised in vitro: the GIP receptor (GIPR), the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor (GCGR). Binding affinity at each is determined by competitive displacement against membranes from cells recombinantly expressing a single human receptor. Functional occupancy is quantified separately at each receptor as cAMP accumulation with EC50 values calculated per receptor, and as beta-arrestin recruitment by enzyme-fragment complementation. Comparative potency across the three receptors is expressed only as a ratio of these in-vitro readings.

Receptor binding affinity and displacement assays at GIPR, GLP-1R and GCGR membrane preparations
cAMP accumulation and beta-arrestin recruitment assays in transfected cell lines expressing one receptor at a time
Reference standard for HPLC and LC-MS method development, purity assignment and mass confirmation
Peptide stability and solubility characterisation under defined buffer, pH and storage conditions
Selectivity-profiling panels comparing EC50 values across the three recombinant receptor systems
Gene- or protein-expression assays in cultured recombinant cell lines carrying single-receptor constructs

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What analytical identity data accompanies the vial?

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